Laboratory Publications




 



  1. Hingorani, V.J., Tobias, D.T., Henderson, J.T. and Ho, Y.K. "Chemical cross-linking of bovine retinal transducin and cGMP phosphodiesterase."
    Journal of Biological Chemistry 263, 6916-6926, 1988.

  2. Benight, A.S., Wang, Y., Amaratunga, M., Chattopadhyaya R., Henderson, J.T., Hanlon, S. and Ikuta S. "Conformation and dynamics of a left-handed Z-DNA hairpin: Studies of d(CGCGCGTTTTCGCGCG) in solution." Biochemistry 28, 3323-3332, 1989.

  3. Wilson, D.H., Price, H.L., Henderson, J.T., Hanlon, S.M. and Benight, A.S. "Structure and Dynamics of M13mp19 Circular Single Strand DNA: Effects of Ionic Strength." Biopolymers 29(2), 357-76 (1990).

  4. Henderson, J.T., Benight, A.S. and Hanlon S.M. "A Semi-Micromethod for the determination of the Extinction Coefficients of Duplex and Single-Stranded DNA." Analytical Biochemistry 201(1), 17-29 (1992).

  5. Henderson, J.T. , Seniuk, N., and Roder J.C. "The gene for ciliary neurotrophic factor maps distal to CD-5 and Ly-10 on Murine Chromosome 19. " Mouse Genome, 91(3), 561-563 (1993).

  6. Madarnas, A.R., Henderson, J.T. and Roder J.C. "The NMDA receptor subunit 2b locus (Nmdar2b) maps to the distal end of murine chromosome 6. " Mammalian Genome, 5(2), 115-166. (1994).

  7. Henderson, J.T. , Seniuk, N., and Roder J.C. "Localization of CNTF immunoreactivity to neurons and astroglia in the CNS." Molecular Brain Research, 22(1-4), 151-165 (1994).

  8. Seniuk, N.A., Henderson, J.T., W.G. Tatton and Roder, J.C." Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl." Journal of Neuroscience Research, 37(2), 278-286 (1994).

  9. Henderson, J.T. , Seniuk, N.A., Richardson, P.M., Gauldie, J. and Roder, J.C., "Systemic administration of ciliary neurotrophic factor induces cachexia in rodents." Journal of Clinical Investigation, 93(6), 2632-2638 (1994).

  10. Seniuk, N.A., Henderson, J.T. and Roder, J.C. "Neurons express CNTF mRNA in the early postnatal period and adult rat brain." Journal of Neuroscience Research, 41(5), 663-76 (1995).

  11. Doering, L.C., Roder, J.C. and Henderson, J.T. "Ciliary Neurotrophic Factor promotes the terminal differentiation of v-myc immortalized sympathoadrenal progenitor cells in vivo." Developmental Brain Research, 89, 56-66 (1995).

  12. Henkemeyer, M., Orioli, D., Henderson, J.T., Saxton, T.M., Roder, J., Pawson, T., and Klein R., "Nuk controls pathfinding of commissural axons in the mammalian central nervous system." Cell 86, 35-46 (1996).

  13. Henderson, J.T., Mullen, B.J., and Roder, J.C. "Physiologic effects of CNTF induced wasting." Cytokine, 8(10), 784-793, 1996.

  14. Jia, Z-P. , Agopyan, N., Miu, P., Xiong, Z., Henderson, J.T., Gerlai, R., Taverna, F., Velumian, A, MacDonald, J., Carlen, P., Abramow-Newerly, W. and Roder, J.C. "Enhanced LTP in mice deficient in the AMPA receptor; GluR2." Neuron, 17, 945-956, 1996.

  15. Henderson, J.T. , Javaheri, M., Kopko, S. and Roder J.C. "Reduction of lower motor neuron disease in wobbler mice by N-acetyl-L-cysteine." Journal of Neuroscience, 16(23),7574-7582, 1996.
    Go to Virtual Paper    .

  16. Lu Y-M., Jia Z-P. Janus, C., Henderson, J.T., Gerlai, R., Wojtowicz, M. and Roder J.C. "Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP), but normal CA3-LTP." Journal of Neuroscience 17(13), 5196-5205, 1997.

  17. Ramer, M.S., Kawaja M.D., Henderson J.T., Roder J.C., Bisby M.A. " Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice." Neuroscience Letters 251(1),53-6, 1998.

  18. Gerlai, R., Henderson, J.T., Roder J.C., and Jia, Z-P. "Multiple behavioral abnormalities in GluR2 mutant mice exhibiting enhanced LTP." Brain Behavioral Research 95(1), 37-45, 1998.

  19. Hakem R., Hakem A,Duncan G.S., Henderson J.T, Woo M., Soengas M.S., Elia A., de la Pompa J.S., Kagi D., Khoo W., Potter J., Yoshida R., Kaufman S.A., Lowe S.W., Penninger J.M. and Mak T.W. "Differential requirement for caspase 9 in apoptotic pathways in vivo." Cell 94, 339-352, 1998.

  20. Jia, Z-P., Lu, Y-M., Henderson, J.T., Taverna, Romano, C., Abramow-Newerly, W., Wojtowicz J.M. and Roder, J.C. "Selective abolition of the NMDA component of long term potentiation in mice lacking mGluR5." Learning and Memory 5, 331-343, 1998.

  21. Wallace M.J., Fladd C.F., Batt J., Henderson J.T., Skarnes W. and Rotin D. "Neuronal defects and posterior pituitary hypoplasia in mice lacking the receptor tyrosine phosphatase PTP sigma." Nature Genetics, 21(3), 334-8, 1999.

  22. Lomaga M.A*, Henderson J.T.* , Elia A.J., Robertson J. Noyce R.S., Yeh W-C., and Mak T.W., "Traf6-deficency results in exencephaly and is required for apoptosis within the developing central nervous system." Journal of Neuroscience, 20(19), 7382-93, 2000.

  23. Sakai, R.*, Henderson J.T.* , O'Bryan J.P., Saxon T.M., and Pawson T. "The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the development of sensory and sympathetic neurons." Neuron, 28, 819-833, 2000.

  24. Iihara K., Joo D.T., Henderson J., Sattler R., Taverna F.A., Lourensen S., Orser B.A., Roder J.C. and Tymianski M., "The influence of Glutamte receptor 2 expression on excitotoxicity in GluR2 null mice. " Journal of Neuroscience, 21(7), 2224-39, 2001.

  25. Henderson J.T., Georgiou, J., Jia Z.P., Robertson J., Elow S., Roder J.C. and Pawson T., "The receptor tyrosine kinase EphB2 regulates NMDA-dependent postnatal synaptic plasticity." Neuron, 32(6), 1041-1056, 2001.

  26. Karam S.D., Dottori M., Ogawa K., Henderson J.T., Boyd A.W., Pasquale E.B. and Bothwell M., "EphA4 is not required for Purkinje cell compartmentation." Developmental Brain Research,135(1-2), 29-38, 2002.

  27. Batlle E., Henderson J.T., Sancho E., Huls G., Meeldijk J., Robertson J., Wetering M.V., Pawson T and Clever H. "Beta-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EPHB/EphrinB." Cell, 111, 251-263, 2002.

  28. Laposa R.R., Henderson J.T., Giovannoni R., Servadio A. and Wells P.G. "Tetracycline-dependent regulation of formamidopyrimidine DNA glycosylase in transgenic mice conditionally reduces oxidative DNA damage in vivo." FASEB Journal, 17(10), 1343-1345, 2003.

  29. G. Hamarneh , J. Chen, B. Neiman, J. Henderson, M. Henkelman. "Segmentation, Registration, and Deformation Analysis of 3D MR Images of Mice." Medical Image Computing and Computer-Assisted Intervention (MICCAI 6th), ISBN 3-540-20464-4, vol. 2879, 878-885, 2003.

  30. Laposa R.R., Henderson J.T., Xu E.E. and Wells P.G. "ATM-null mice exhibit radiation-induced birth defects and a novel form of programmed cell death indicative of teratologic suppressor function." FASEB J, 18(7), 896-8, 2004.

  31. Kovacevic N., Chen X.J., Sled J., Henderson J.T., and Henkelman R.M "Deformation-based representations of groupwise average and variability." Medical Image Computing and Computer-Assisted Intervention (MICCAI 7th), ISBN 3-540-20464-4, vol. 3216, 615-622, 2004.

  32. Kovacevic N., Henderson J.T., Chan E., Lifshitz N., Bishop J., Evans A.C., Henkelman R.M., Chen X.J. "A Three-dimensional MRI Atlas of the Mouse Brain with Estimates of the Average and Variability." Cerebral Cortex, 15(5), 639-45, 2005 (Epub Sept. 1, 2004).

  33. Chen X.J., Kovacevic N., Lobaugh N.J., Sled J.G., Henkelman R.M., and Henderson J.T. "Neuroanatomical differences between mouse strains as shown by high-resolution 3D MRI." Neuroimage 29(1), 99-105, 2006, (Epub Aug. 9, 2005).

  34. Chan E., Kovacevic N., Ho S.K.Y., Henkelman R.M., and Henderson J.T. "Development of a high resolution three dimensional surgical atlas of the murine head for strains 129S1/SvImJ and C57Bl/6J using magnetic resonance imaging and micro-computed tomography and micro-CT." Neuroscience, Volume 144(2), 604-615, 2007 (Epub Nov. 13, 2006) (Atlas).

  35. Xie G., Clapcote S., Nieman B.J., Tallerico T., Huang Y., Vukobradovic I., Cordes S.P., Osborne L.R., Rossant J., Sled J.G., Henderson J.T., and Roder J.R. "Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependant calcium channel, CACNA1A." Genes Brain and Behavior, Oct;6(8), 717-27, 2007 (Epub Mar 21, 2007).

  36. Hui K., Kucera J., and Henderson J.T., "Differential sensitivity of skeletal and fusimotor neurons to Bcl-2 mediated apoptosis during neuromuscular development." Cell Death Differ. 2008 Apr;15(4):691-9. Epub 2007 Dec 21.

  37. Henderson J.T. "Lazarus's gate: Challenges and potential of epigenetic reprogramming of somatic cells." Clin Pharmacol Ther. 2008 Jun;83(6):889-93. doi: 10.1038/clpt.2008.51. Epub 2008 Mar 26.

  38. Kanungo A.K., Hao Z., Elia A.J., Mak T.W., and Henderson J.T., "Inhibition of apoptosome activation protects injured motor neurons from cell death." J Biol Chem. 2008 Aug 8;283(32):22105-12. doi: 10.1074/jbc.M800988200. Epub 2008 Jun 10.

  39. Wells P.G., McCallum G.P., Chen C.S., Henderson J.T., Lee C.J.J., Perstin J., Preston T., Wiley M.J. and Wong A.W., "Oxidative stress in developmental origins of disease: Teratogenesis, neurodevelopmental deficits and cancer." Toxicol Sci. 2009 Mar;108(1):4-18. doi: 10.1093/toxsci/kfn263. Epub 2009 Jan 6. Review.

  40. Kanungo A.K., Liadis N., Robertson J., Woo M. and Henderson J.T., "Excitatory tonus is required for the survival of granule cell precursors during postnatal development within the cerebellum." Neuroscience. 2009 Feb 18;158(4):1364-77. doi: 10.1016/j.neuroscience.2008.10.062. Epub 2008 Nov 8.

  41. Kanawaty A. and Henderson J.T., "Genomic analysis of induced pluripotent stem (iPS) cells: routes to reprogramming." Bioessays. 2009 Feb;31(2):134-8. doi: 10.1002/bies.200800204.

  42. Hui K., Liadis N., Robertson J., Kanungo A. and Henderson J.T., "Calcineurin inhibition enhances motor neuron survival following injury." J Cell Mol Med. 2010 Mar;14(3):671-86. doi: 10.1111/j.1582-4934.2009.00715.x. Epub 2009 Feb 20. Erratum format corrected: J Cell Mol Med. 2010 Jun;14(6B):1869-73.

  43. Ho, SKY, Kovacevic N., Henkelman R.M., Boyd A., Pawson T. and Henderson J.T., "EphB2 and EphA4 receptors regulate formation of the principle inter-hemispheric tracts of the mammalian forebrain." Neuroscience. 2009 Jun 2;160(4):784-95. doi: 10.1016/j.neuroscience.2009.03.013. Epub 2009 Mar 13.

  44. Preston, T. J., Henderson, J. T., McCallum, G. P., and Wells, P. G., "Base excision repair of reactive oxygen species-induced 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs." Mol Cancer Ther. 2009 Jul;8(7):2015-26. doi: 10.1158/1535-7163.MCT-08-0929. Epub 2009 Jun 30.

  45. Clapcote S.J., Duffy S., Xie G., Kirshenbaum G., Bechard A.R., Schack V.R., Petersen J., Sinai L., Saab B.J., Lerch J.P., Minassian B.A., Ackerley C.A., Sled J.G., Cortez M.A., Henderson J.T., Vilsen B.,and Roder J.C., "Mutation I810N in the {alpha}3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS." Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14085-90. doi: 10.1073/pnas.0904817106. Epub 2009 Aug 3.

  46. Hui K.K.W. and Henderson J.T., "Polyglutamine neuropathies: Animal models to molecular mechanisms." Chapter 17 of Endogenous Toxins: Targets for Disease Treatment and Prevention, O'Brien and Bruce (Eds.) Wiley Publishers 2009.

  47. Wells P.G., McCallum G.P., Lam K.C.H., Henderson J.T. and Ondovcik S.L., "Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits." Birth Defects Res C Embryo Today. 2010 Jun;90(2):103-9. doi: 10.1002/bdrc.20177.

  48. Hui K.K.W. , Kanungo A.K., Elia A.J. and Henderson J.T., "Caspase-3 deficiency reveals a physiologic role for Smac/DIABLO in regulating programmed cell death." Cell Death and Diff. 2011 Nov;18(11):1780-90. doi: 10.1038/cdd.2011.50. Epub 2011 May 20.

  49. Mansouri A., Min W., Cole C.J., Josselyn S.A., Henderson J.T., van Eede M., Henkelman M.R., Ackerley C., Roifman C.M. and Grunebaum E., "Cerebellar abnormalities in purine nucleoside phosphorylase deficient mice." Neurobiology of Disease 2012 Aug;47(2):201-9. doi: 10.1016/j.nbd.2012.04.001. Epub 2012 Apr 11.

  50. Shalviri A., Cai P., Rauth A.M., Henderson J.T. And Wu X.Y., "Evaluation of new bi-functional terpolymeric nanoparticles for simultaneous in vivo optical imaging and chemotherapy of breast cancer." Drug Delivery and Translational Research: 2012,Volume 2, Issue 6: 437-453.

  51. Shuhendler A.J., Prasad P., K.K. W. Hui, Henderson J.T., Rauth A.M. and Wu X.Y., "Matrigel alters the pathophysiology of orthotopic human breast adenocarcinoma xenografts with implications for Nanomedicine Evaluation." Nanomedicine. 2013 Aug;9(6):795-805. doi: 10.1016/j.nano.2013.01.005. Epub 2013 Feb 19.

  52. Fardell J.E., Zhang J., De Souza R., Vardy J., Johnston I., Allen C., Henderson J.T. and Piquette-Miller M., "The impact of sustained and intermittent docetaxel chemotherapy regimens on cognition and neural morphology in healthy mice," Pharmacotherapy 2013 Oct 8. [Epub ahead of print] 10.1007/s00213-013-3301-8.

  53. Ashraf T., Jiang W., Hoque T., Henderson J.T., Wu C. and Bendayan R., "Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120 -mediated brain inflammation," J Neuroinflammation. 2014 May 16;11:91.

  54. Durk M.R., Han K., Chow E.C.Y., Ahrens R., Henderson J.T., Fraser P.E. and Pang S.K., "1-alpha,25-Dihydroxyvitamin D3 Reduces Cerebral Amyloid-beta Accumulation and Improves Cognition in Mouse Models of Alzheimer's Disease," J Neurosci. 2014 May 21;34(21):7091-101.

  55. Li J., Cai P., Shalviri A., Henderson J.T., He C., Foltz W., Prasad P.,Brodersen P., Chen Y., DaCosta R., Rauth A. M. and Wu X.Y., " A Multifunctional Polymeric Nanotheranostic System Delivers Doxorubicin and Imaging Agents Across the Blood-Brain Barrier Targeting Brain Metastases of Breast Cancer," ACS Nano. 2014 Oct 13. [Epub ahead of print].

  56. Arsenault J., Nagy A., Henderson J.T., O'Brien J.A, "Regioselective Biolistic Targeting in Organotypic Brain Slices Using a Modified Gene Gun," J Vis Exp. 2014 Oct.24;(92). e52148. doi: 10.3791/52148.  JOVe link.

  57. Henderson JT, Piquette-Miller M., "Blood-brain barrier: An impediment to neuropharmaceuticals," Clinical Pharmacology and Therapeutics 2015 Apr;97(4):308-13. doi: 10.1002/cpt.77. Epub 2015 Feb 24.PMID: 25670372.

  58. Huroy S., Kanawaty A., Magomedova L., Cummins C.L., George S.R., van der Kooy D. and Henderson J.T., "EphB2 Reverse Signaling Regulates Learned Opiate Tolerance via Hippocampal Function," Behav. Brain Res. 2015 Sep 22. pii: S0166-4328(15)30196-0. doi: 10.1016/j.bbr.2015.09.023. [Epub ahead of print] Supplemental Material.

  59. S. El Ghamrasni, Cardoso R., Li L., Guturi K.K., Bjerregaard V.A., Liu Y., Venkatesan S., Hande M.P., Henderson J.T., Sanchez O., Hickson I.D., Hakem A. and Hakem R, "Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation," Oncogene 2016 Feb 15. doi: 10.1038/onc.2016.16. [Epub ahead of print]

  60. He C., Cai P., Li J., Zhang T., Lin L., Abbasi A.Z., Henderson J.T., Rauth A.M. and Wu X.Y.,"Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer," J Control Release. 2016 Dec 23;246:98-109. doi: 10.1016/j.jconrel.2016.12.019. [Epub ahead of print]

  61. He C., Li J., Cai P., Ahmed T., Henderson J.T., Foltz W.D., Bendayan R., Rauth A.M. and Wu X.Y.,"Two-Step Targeted Hybrid Nanoconstructs Increase Brain Penetration and Efficacy of the Therapeutic Antibody Trastuzumab against Brain Metastasis of HER2-Positive Breast Cancer," Advanced Func. Mater. 28(9) 1705668. 2018. doi: 10.1002/adfm.201705668. [Epub ahead of print]

  62. Hui K.K.W., Dojo Soeandy C., Chang S., Vizeacoumar F.S., Sun T., Datti A. and Henderson J.T., "Cell-based High Throughput Screen for Small Molecule Inhibitors of Bax Translocation," J Cell Mol Med.2019, Mar;23(3):1784-1797. doi: 10.1111/jcmm.14076. Epub 2018 Dec 13.

  63. Dojo Soeandy C., Salmasi F., Latif M., Elia A.J., Suo N.J. and Henderson J.T., "Endothelin-1-mediated cerebral ischemia in mice: Early cellular events and the role of caspase-3," Apoptosis, Aug;24 (7-8):578-595, 2019. doi: 10.1007/s10495-019-01541-z. [Epub May 9th, 2019].

  64. Zhang T., Lip H., He C., Cai P., Wang Z., Henderson JT., Rauth A.M. and Wu S.X.Y., "Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages," Advanced Health Care Materials 2019 Sep;8(18):e1900543. doi: 10.1002/adhm.201900543. [Epub July 26th, 2019].

  65. Dojo Soeandy C., Elia A.J, Cao Y., Rodgers C., Huang S., Elia A.C. and Henderson J.T., "Necroptotic-Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia," Cellular and Molecular Neurobiology, Aug 25, 2020 doi: 10.1007/s10571-020-00942.

  66. He C., Ahmed T., Abbasi A.Z., Li L.Y., Foltz W.D., Cai P., Knock E., Fraser P.E., Rauth A.M, Henderson J.T and Wu X.Y., "Multifunctional Bioreactive-Nanoconstructs for Sensitive and Accurate MRI of Cerebrospinal Fluid Pathology and Intervention of Alzheimer's Disease," Nano Today, volume 35, Dec. 2020, 100965.

  67. Amini M., Ahmed T., Liu, F.C., Abbasi A., Dojo Soeandy C., Zhang R.X., Prashad P., Cummings C., Rauth A., Henderson J.T. and Wu X.Y, "Exploring the transformability of polymer-lipid hybrid nanoparticles and nanomaterial-biology interplay to facilitate tumor penetration, cellular uptake and intracellular targeting of anticancer drugs," Expert Opin. Drug Deliv., 2021,18(7):991-1004 Epub 2021 Mar 30.

  68. Ahmed T., Liu F.F., Chungsheng He; Abbasi A.Z., Cai P., Rauth A.M., Henderson J.T. and X.Y. Wu, "Optimizing the Design of Blood-Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma," Pharmaceutical Research, 2021, 38(11): 1897-1914. doi: 10.1007/s11095-021-03122-9. Epub 2021 Oct 15.

  69. Hui K.K.*, Latif M.*, DojoSoeandy C., Huang S., Rodgers C.E., Elia A.J. and Henderson J.T., "Cisplatin toxicity in the developing brain displays an absolute requirement for caspase-3," Experimental Neurology, 2022 May; 351:114010. https://doi.org/10.1016/j.expneurol.2022.114010. Epub 2022 Feb 12.

  70. Steinman J., Ovcjak A., Luo Z., Zhang X., Britto L.R., Henderson J.T., Sun H.S. and Feng Z.P., "Transient receptor potential melastatin 2 channels in neurological disorders: Mechanisms and animal models," Advanced Neurology, 2022, 1(1), pg. 1-18. https://doi.org/10.36922/an.v1i1.3.

  71. Ahmed T., Liu F.C.F., Lu B., Lip HY., Park E., Alradwan I., Liu J.F., He C., Zetrini A., Zhang T., Ghavaminejad A., Rauth A.M., Henderson J.T. and Wu X.Y., "Advances in Nanomedicine Design: Multidisciplinary Strategies for Unmet Medical Needs," Molecular Pharmaceutics, 2022, 19(6), pg. 1722-1765. May 19. doi: 10.1021/acs.molpharmaceut.2c00038.

  72. Sangha V., Hoque T.M., Henderson J.T. and Bendayan R., "Novel localization of folate transport systems in the murine central nervous system," Fluids Barriers CNS, 2022 Nov 23;19(1):92. doi: 10.1186/s12987-022-00391-3.

  73. Park E., Li L.Y., He C., Abbasi A.Z., Ahmed T., Foltz W.D., O'Flaherty R., Zain M., Bonin R.P., Rauth A.M., Fraser P.E., Henderson J.T. and Wu S.X.Y., "Brain-Penetrating and Disease Site-Targeting Manganese Dioxide-Polymer-Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways," Adv Sci (Weinh). 2023 Apr;10(12):e2207238. doi: 10.1002/advs.202207238. Online ahead of print.

  74. Eliza R McColl , Henderson J.T and Piquette-Miller M., "Dysregulation of Amino Acid Transporters in a Rat Model of TLR7-Mediated Maternal Immune Activation," Pharmaceutics. 2023 Jul 1;15(7):1857.doi: 10.3390/pharmaceutics15071857.

  75. Zetrini A.E., Lip H-Y., Abbasi A.Z., Alradwan I., Ahmad T., He C., Henderson J.T., Rauth A.M. and Wu S.X.Y., "Remodeling Tumor Immune Microenvironment by Using Polymer-Lipid-Manganese Dioxide Nanoparticles with Radiation Therapy to Boost Immune Response of Castration-Resistant Prostate Cancer," Research (Wash D C). 2023 Oct 3;6:0247. doi: 10.34133/research.0247. eCollection 2023.

  76. Cho T., Wierk A., Gertsenstein M., Rodgers C., Uetrecht J. and Henderson J.T., "Development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions," Toxicologic Sciences 2024, Mar 26;198(2):233-245.doi: 10.1093/toxsci/kfae003.

  77. Yen T.Y., Abbasi A.Z., He C., Li H-Y., Park E., Amini M., Adissu H., Foltz W., Rauth A.M., Henderson J.T. and Wu S.X.Y., "Biocompatible and Bioactivable Terpolymer-Lipid-MnO2 Nanoparticle-Based MRI Contrast Agent for Improving Tumor Detection and Delineation," Materials Today Bio 25 (2024) 100954.

  78. Huang S., Suo N.J., Henderson T.R., Macgregor Jr R.B. and Henderson J.T., "Cellular Transfection using Rapid Decrease in Hydrostatic Pressure," Scientific Reports 2024, 14:4631-6. February 26, 2024. doi.org/10.1038/s41598-024-54463-5,26. Supplemental information.

  79. Cho T., Hayes A., Henderson, J.T. and Uetrecht J., "The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine." Toxicologic Sciences 2024 Aug 1;200(2):382-393
    doi: 10.1093/toxsci/kfae058.

  80. Huang S., Henderson T.R., Dojo Soeandy C., Lezhanska A. and Henderson J.T., "An efficient low cost means of biophysical gene transfection in primary cells." Scientific Reports 2024, Jun 8; 14(1): 13179. doi: 10.1038/s41598-024-62996-y. Published online ahead of print.

  81. Huang C., Hoque Md.T., Qu Q.R., Henderson J.T. and Bendayan R., "Antiretroviral drug dolutegravir induces inflammation at the mouse brain barriers." The FASEB Journal 2024 Jul 15;38(13):e23790. doi: 10.1096/fj.202400558R

  82. Zetrini A.E., Abbasi A.Z., He C., Lip H.-Y., Alradwan I., Rauth A.M., Henderson J.T. and Wu S.X.Y., "Targeting DNA damage repair mechanism by using RAD50-silencing siRNA nanoparticles to enhance radiotherapy in triple negative breast cancer" Materials Today Bio, 2024 Aug 16:28:101206. doi.org/10.1016/j.mtbio.2024.101206

  83. Li L-Y, Park E., He C., Abbasi A.Z., Henderson J.T., Fraser P.E., Uetrecht J.P., Rauth A.M. and Wu S.X.Y, "Evaluation of the biodistribution and preliminary safety profile of a novel brain-targeted manganese dioxide-based nanotheranostic system for Alzheimer's disease," Nanotoxicology 2024 Jun;18(4):315-334. doi: 10.1080/17435390.2024.2361687.



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